Stem cell platform engineered by U of T researchers sheds new light on beginnings of human development

PhD candidate Mukul Tewary is the lead author of a paper detailing the technology that enables human embryonic stem cells to self-organize into a structure with embryo-like features (photo courtesy of Ontario Institute for Regenerative Medicine)

Researchers at University of Toronto’s Medicine By Design have engineered a new platform to study the earliest stages of human development in the lab, pulling back the curtain on key biological processes that until now have taken place inside the uterus, beyond the gaze of scientists.

Believed to be the first of its kind in Canada, the technology enables human embryonic stem cells to self-organize into a structure with embryo-like features, including the early precursors of organs such as the brain, the heart and the liver.

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